ro5-4864 (Fluka Chemical)
Structured Review
Ro5 4864, supplied by Fluka Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ro5-4864/ro5+4864/pmc07572456-179-6-10
Average 90 stars, based on 1 article reviews
Images
Related Articles
other:Article Title: Peripheral benzodiazepine receptors in androgen sensitive dunning rat prostatic adenocarcinoma. Article Snippet: Peripheral benzodiazepine receptor (PBZr) binding sites in isolated mitochondrial (m-fractions) and microsomal fractions (p-fractions) from androgen sensitive R-3327 Dunning G and H tumors were studied.. Binding in both mand p-fractions of these tumors was specific, saturable, and of high affinity.. A very high density of PBZr was found in m-fraction from both types of tumors. Article Title: Effect of the triakontatetraneuropeptide (TTN) on corticosteroid secretion by the frog adrenal gland. Article Snippet: Ro5-4864 was obtained from Article Title: Elevated concentrations of mitochondrial peripheral benzodiazepine receptors in ovarian tumors. Article Snippet: Us ing PK 11195, a high affinity l igand for peripheral benzodiazepine receptor (PBZr) binding sites in isolated mitochondria (m-fraction) and microsomal fraction (p-fraction) from human ovaries and ovarian tumors were studied.. Binding in both m and p-fractions from ovaries and tumors were saturable and of high affinity.. The PBZr density in mand p-fractions from ovaries was very similar whereas the binding in m-fraction in ovarian tumors was nearly 3-fold higher than p-fraction. Article Title: Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam Article Snippet: MTBE was purchased from Fisons, Loughborough; Ro5‐4864 was purchased from Article Title: Translocator protein (18 kDa) mediates the pro-growth effects of diazepam on Ehrlich tumor cells in vivo. Article Snippet: Diazepam (Cristália do Brasil S/A), Article Title: Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity. Article Snippet: The consequences of the neurotoxic insult induced by 3,4-methylenedioxymethamphetamine (MDMA, an amphetamine derivative with specific action on the serotonergic system) were compared with those of methamphetamine (a derivative with specific action on dopaminergic system) in rats.. Both drugs induced a very similar loss of body weight, especially evident 24 h after treatment.. Their hyperthermic profile was also very similar and was dependent on ambient temperature, corroborating the thermo-dysregulatory effect of both substances. Article Title: Octadecaneuropeptide ODN prevents hydrogen peroxide-induced oxidative damage of biomolecules in cultured rat astrocytes. Article Snippet: Oxidative stress, associated with a variety of disorders including neurodegenerative diseases, is a major cause of cellular dysfunction and biomolecule damages which play a crucial role in neuronal apoptosis.. Astrocytes specifically synthesize and release endozepines, a family of regulatory peptides, including the octadecaneuropeptide ODN.. We have recently shown that ODN is a potent glioprotective agent that prevents hydrogen peroxide (H2O2)-induced oxidative stress and apoptosis. |
